The estate's history dates back to 1692. German settler Willem Barend Lubbe received the land from Simon van der Stel and initially named the farm De Wolwedans. The estate received its present name after Johannes Henoch Neethling, who became owner in the 19th century. The historic manor house was completed in 1814 under the direction of Maria Marais and remains a defining feature of Neethlingshof today.

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In 1985, German banker Hans Joachim Schreiber acquired the estate and had the buildings and vineyards extensively renovated. Since 2022, Neethlingshof has belonged to Iwayini, the South African subsidiary of the French family group Grands Chais de France. The estate's long history is therefore now combined with an internationally oriented approach to winemaking.

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The vineyards are spread across eight distinct sites with varying elevations, gradients and aspects. The main soil types include Tukulu, Oakleaf and Villafonté. Many vineyards face south or south-west and are reached in the afternoon by cool air currents from the Atlantic and Indian Oceans. This allows the grapes to ripen slowly and develop fruit, acidity and structure in a balanced way.

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The estate grows Pinotage, Cabernet Sauvignon, Merlot, Cabernet Franc, Malbec, Petit Verdot and Shiraz among others. White varieties include Sauvignon Blanc, Chardonnay, Gewürztraminer, Riesling, Chenin Blanc and Viognier. The Estate Range comprises single-varietal red wines, white wines and Rosé, all produced and bottled entirely on the estate. The range is complemented by traditionally made Cap Classique sparkling wines.

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The Short Story Collection links individual wines with the history and natural environment of the estate. Owl Post Pinotage recalls the introduction of owls to control pests naturally, while the red blend The Caracal refers to the protection of native wildlife. Another speciality is The Maria Noble Late Harvest from an old vineyard planted in 1986, named after Maria Marais and her role in the history of the manor house.

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Since 2003, Neethlingshof has increasingly focused on protecting natural habitats and promoting biodiversity. The estate is a WWF Conservation Champion and follows vegan practices in both vineyard and cellar. At Vin Africa you will find traditional Neethlingshof wines from Stellenbosch that combine varied soils, cooling coastal influences and the established identity of this historic estate.